Mission and strategy
The basis of the strategic plan of MHeNS is that the research of the school, and thus of the divisions, is converged on three translational area:
Neurodegeneration, neuromodulation and Social Neuroscience.
Our approach is to create a specific translational research focus i.e. to perform research in the basic mechanisms underlying neuropsychiatric and neurological diseases giving rise to their neuropsychiatric, neurological and clinical expression, as well as treatment stategies.
To gain insight in molecular and cellular biological mechanisms that lead to neurodegeneration, we focus on the development of new therapeutic approaches of neurological and psychiatric diseases on basis of cellular and animal models. On the other hand clinical services for adult neurodegenerative disorders receive new input on early detection and intervention from research performed in neuropsychology and neuroimaging.
Discovery animal research on the impact of neuromodulation of higher cerebral functions including depression, pain, fine motor function, bladder incontinence and addiction is translated to the clinic, resulting in neurosurgical experimental interventions and the treatment of pain. In the division 3 research is focused on receptors and diseases with impaired intra- and intercellular signal transduction.
Social Neuroscience refers to the science of person-environment interactions and gene-environment interactions(ecogenetcis) which are underlying disorders of salience attribution, mood regulations and impulsivity, using a variety of neuroscience paradigms including animal research, molecular ecogenetics, neuroimaging and experimental psychology and psychopharmacology. All this research is meant to feed the early recognition and treatment of psychiatric disorders, in particular psychosis and depression.